Dr Murphy'S Research Paper
He is co-PI with Zak Kohane of the next generation platform, Patient-centered Information Commons BD2K Center of Excellence, which will integrate data sourced not only from the EHR, but also social medial, “omic” inputs, radiology reports, and environmental feeds and co-Investgiator on the PCORI-supported Accessible Research Commons for Health (ARCH) program, both of which are based at DBMI.Authors: Estiri H, Klann JG, Weiler SR, Alema-Mensah E, Joseph Applegate R, Lozinski G, Patibandla N, Wei K, Adams WG, Natter MD, Ofili EO, Ostasiewski B, Quarshie A, Rosenthal GE, Bernstam EV, Mandl KD, Murphy SN.The strong plasmon bands of noble metal nanoparticles make them ideal for biological sensing and imaging applications.We have used the elastic light scattering properties of gold nanorods as "nano strain gauges" to measure the deformation of soft matrices by living cells.The inelastic light scattering (Raman) properties of gold nanorods can be used to interrogate the local chemical environment of the nanorods.Irradiation into nanorod plasmon bands causes large temperature jumps in the local environment, which we have exploited as a way to kill multidrug-resistant bacteria (once the nanorods are surface-modified to recognize the bacteria). How are nanoparticles distributed and modified in complex biological systems?One aspect of her research program focuses on how situational cues in academic, organizational, and group environments affect people’s cognition, motivation, performance, and physiology, with an eye toward intervention.
From 1993-2009 Professor Murphy was a faculty member in the Department of Chemistry and Biochemistry at the University of South Carolina.
in Social Psychology from Stanford University in 2007, mentored by Claude Steele and Carol Dweck.
She currently focuses on three programs of research.
From 1990-1993, she was first an NSF and then an NIH postdoctoral fellow at the California Institute of Technology.
Our primary goal is to develop inorganic nanomaterials for biological and energy-related applications, and understand the chemical interactions of these nanomaterials with their surroundings.