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In aggregate, all tested genetic variants accounted for 8 to 25% of variation in male and female same-sex sexual behavior, and the genetic influences were positively but imperfectly correlated between the sexes [genetic correlation coefficient (= 0.63; 95% confidence intervals, 0.48 to 0.78].
These aggregate genetic influences partly overlapped with those on a variety of other traits, including externalizing behaviors such as smoking, cannabis use, risk-taking, and the personality trait “openness to experience.” Additional analyses suggested that sexual behavior, attraction, identity, and fantasies are influenced by a similar set of genetic variants ( 0.83); however, the genetic effects that differentiate heterosexual from same-sex sexual behavior are not the same as those that differ among nonheterosexuals with lower versus higher proportions of same-sex partners, which suggests that there is no single continuum from opposite-sex to same-sex preference.
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Overlap with genetic influences on other traits provides insights into the underlying biology of same-sex sexual behavior, and analysis of different aspects of sexual preference underscore its complexity and call into question the validity of bipolar continuum measures such as the Kinsey scale. contributed to data acquisition and analysis of the 23and Me dataset. Across human societies and in both sexes, some 2 to 10% of individuals report engaging in sex with same-sex partners, either exclusively or in addition to sex with opposite-sex partners. contributed to data acquisition and analysis of the MGSOSO data. Twin and family studies have shown that same-sex sexual behavior is partly genetically influenced, but previous searches for the specific genes involved have been underpowered to detect effect sizes realistic for complex traits. Its no-nonsense, minimal interface gets out of your way. Writer packs a ton of powerful features into its sleek design. All of your writing is saved online so that it's available no matter where you are or what computer you use.You never have to worry about running out of storage space. Multiple revisions of every document are saved automatically as you write so you can go back to your document as it existed a day, a week, or years ago.Three of the loci were significant in a meta-analysis of smaller, independent replication samples. Although only a few loci passed the stringent statistical corrections for genome-wide multiple testing and were replicated in other samples, our analyses show that many loci underlie same-sex sexual behavior in both sexes. contributed to data acquisition and analysis of the Add Health data. It's the perfect companion tool that lets you focus and get your drafts done. Writer lets you focus on what's important: your words.Writer eliminates distractions so that you can concentrate, be more productive, and get your writing done. Writer lets you save an unlimited number of documents of any length.And you can set a word or character count goal or a timer.Writing goals keep you focused, on track, and make sure you can hit your daily word count.