Short Case Study Of Depression
After 48 hours she began to show an interest in her pastimes and after 72 hours began cooking meals and snacks for patients and staff.
She was discharged after 5 days and continued to improve for several weeks.
He was readmitted and a second course of ketamine at 30 mg/h (0.3 mg/kg/h) was given.
Nursing staff reported improvement over the 5 days similar to that seen on the first admission.
This dose was assumed to be a therapeutic dose and was maintained for 5 days.However, the patient and his mother felt that there was little change.It was about 10 days after the completion of the second infusion cycle that he reported that “the fog has lifted,” and his mood rapidly improved after that.At this level, the patient was “a bit heady” but did not hallucinate.Nursing staff and family noted a positive improvement in the patient after 24 hours, particularly a decrease in fluctuation of mood.If hallucinations occurred, the dose was to be reduced.The patient's normal medications were continued as it was feared that stopping them may result in a severe depressive episode.Patients were able to eat, drink, watch television, or read.They could feel inebriated and/or unsteady when walking.Ketamine was commenced at 20 mg/h (0.2 mg/kg/h) and titrated to 30 mg/h (0.3 mg/kg/h).At this dose, the patient said he felt “a bit heady” but he did not hallucinate.